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Pore-forming spider venom peptides show cytotoxicity to hyperpolarized cancer cells expressing K(+) channels: A lentiviral vector approach
Recent studies demonstrated the upregulation of K(+) channels in cancer cells. We have previously found that a pore-forming peptide LaFr26, purified from the venom of the Lachesana sp spider, was selectively incorporated into K(+) channel expressing hyperpolarized cells. Therefore, it is expected th...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6461346/ https://www.ncbi.nlm.nih.gov/pubmed/30978253 http://dx.doi.org/10.1371/journal.pone.0215391 |