siRNA-silencing of CD40 attenuates unilateral ureteral obstruction-induced kidney injury in mice

BACKGROUND: The costimulatory CD40-CD40L pathway plays a role in kidney inflammation. We have previously reported that renal CD40 upregulation precedes cellular interstitial infiltrate and fibrosis in the unilateral ureteral obstruction (UUO) model. Here we sought to evaluate whether the administrat...

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Detalles Bibliográficos
Autores principales: Narváez, Alonso, Guiteras, Roser, Sola, Anna, Manonelles, Anna, Morote, Juan, Torras, Juan, Grinyó, Josep M., Cruzado, Josep M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6461348/
https://www.ncbi.nlm.nih.gov/pubmed/30978213
http://dx.doi.org/10.1371/journal.pone.0215232

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6461348/
https://www.ncbi.nlm.nih.gov/pubmed/30978213
http://dx.doi.org/10.1371/journal.pone.0215232

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