Inhalation treatment of cystic fibrosis with lumacaftor and ivacaftor co-delivered by nanostructured lipid carriers

Cystic fibrosis (CF), a most deadly genetic disorder, is caused by mutations of CF transmembrane receptor (CFTR) - a chloride channel present at the surface of epithelial cells. In general, two steps have to be involved in treatment of the disease: correction of cellular defects and potentiation to...

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Detalles Bibliográficos
Autores principales: Garbuzenko, O.B., Kbah, N., Kuzmov, A., Pogrebnyak, N., Pozharov, V., Minko, T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6461390/
https://www.ncbi.nlm.nih.gov/pubmed/30677435
http://dx.doi.org/10.1016/j.jconrel.2019.01.025

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6461390/
https://www.ncbi.nlm.nih.gov/pubmed/30677435
http://dx.doi.org/10.1016/j.jconrel.2019.01.025

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