An ESCRT-LEM protein surveillance system is poised to directly monitor the nuclear envelope and nuclear transport system

The integrity of the nuclear membranes coupled to the selective barrier of nuclear pore complexes (NPCs) are essential for the segregation of nucleoplasm and cytoplasm. Mechanical membrane disruption or perturbation to NPC assembly triggers an ESCRT-dependent surveillance system that seals nuclear p...

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Detalles Bibliográficos
Autores principales: Thaller, David J, Allegretti, Matteo, Borah, Sapan, Ronchi, Paolo, Beck, Martin, Lusk, C Patrick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2019
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6461442/
https://www.ncbi.nlm.nih.gov/pubmed/30942170
http://dx.doi.org/10.7554/eLife.45284

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6461442/
https://www.ncbi.nlm.nih.gov/pubmed/30942170
http://dx.doi.org/10.7554/eLife.45284

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