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Fludarabine as an Adjuvant Improves Newcastle Disease Virus-Mediated Antitumor Immunity in Hepatocellular Carcinoma

In addition to direct oncolysis, oncolytic viruses (OVs) also induce antitumor immunity, also called viro-immunotherapy. Limited viral replication and immune-negative feedback are the major hurdles to effective viro-immunotherapy. In this study, we found that use of an adjuvant of fludarabine, a che...

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Detalles Bibliográficos
Autores principales: Meng, Gang, Fei, Ziwei, Fang, Mingyue, Li, Binghua, Chen, Anxian, Xu, Chun, Xia, Mao, Yu, Decai, Wei, Jiwu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6461577/
https://www.ncbi.nlm.nih.gov/pubmed/31011625
http://dx.doi.org/10.1016/j.omto.2019.03.004