HMGB1 is a Central Driver of Dynamic Pro-inflammatory Networks in Pediatric Acute Liver Failure induced by Acetaminophen

Acetaminophen (APAP) overdose (APAPo) is predominant in the NIH Pediatric Acute Liver Failure (PALF) Study. We assayed multiple inflammatory mediators in serial serum samples from 13 PALF survivors with APAPo + N-acetylcysteine (NAC, the frontline therapy for APAPo), 8 non-APAPo + NAC, 40 non-APAPo...

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Detalles Bibliográficos
Autores principales: Zamora, Ruben, Barclay, Derek, Yin, Jinling, Alonso, Estella M., Leonis, Mike A., Mi, Qi, Billiar, Timothy R., Simmons, Richard L., Squires, Robert H., Vodovotz, Yoram
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6461628/
https://www.ncbi.nlm.nih.gov/pubmed/30979951
http://dx.doi.org/10.1038/s41598-019-42564-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6461628/
https://www.ncbi.nlm.nih.gov/pubmed/30979951
http://dx.doi.org/10.1038/s41598-019-42564-5

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