TBX3 represses TBX2 under the control of the PRC2 complex in skeletal muscle and rhabdomyosarcoma

TBX2 and TBX3 function as repressors and are frequently implicated in oncogenesis. We have shown that TBX2 represses p21, p14/19, and PTEN in rhabdomyosarcoma (RMS) and skeletal muscle but the function and regulation of TBX3 were unclear. We show that TBX3 directly represses TBX2 in RMS and skeletal...

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Detalles Bibliográficos
Autores principales: Oh, Teak-Jung, Adhikari, Abhinav, Mohamad, Trefa, Althobaiti, Aiysha, Davie, Judith
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6461654/
https://www.ncbi.nlm.nih.gov/pubmed/30979887
http://dx.doi.org/10.1038/s41389-019-0137-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6461654/
https://www.ncbi.nlm.nih.gov/pubmed/30979887
http://dx.doi.org/10.1038/s41389-019-0137-z

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