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Structural bases of peptidoglycan recognition by lysostaphin SH3b domain

Staphylococcus simulans lysostaphin cleaves pentaglycine cross-bridges between stem peptides in the peptidoglycan of susceptible staphylococci, including S. aureus. This enzyme consists of an N-terminal catalytic domain and a cell wall binding domain (SH3b), which anchors the protein to peptidoglyca...

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Detalles Bibliográficos
Autores principales: Mitkowski, Paweł, Jagielska, Elżbieta, Nowak, Elżbieta, Bujnicki, Janusz M., Stefaniak, Filip, Niedziałek, Dorota, Bochtler, Matthias, Sabała, Izabela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6461655/
https://www.ncbi.nlm.nih.gov/pubmed/30979923
http://dx.doi.org/10.1038/s41598-019-42435-z