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Direct observation of coordinated DNA movements on the nucleosome during chromatin remodelling

ATP-dependent chromatin remodelling enzymes (remodellers) regulate DNA accessibility in eukaryotic genomes. Many remodellers reposition (slide) nucleosomes, however, how DNA is propagated around the histone octamer during this process is unclear. Here we examine the real-time coordination of remodel...

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Detalles Bibliográficos
Autores principales: Sabantsev, Anton, Levendosky, Robert F., Zhuang, Xiaowei, Bowman, Gregory D., Deindl, Sebastian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6461674/
https://www.ncbi.nlm.nih.gov/pubmed/30979890
http://dx.doi.org/10.1038/s41467-019-09657-1