Cargando…
Direct observation of coordinated DNA movements on the nucleosome during chromatin remodelling
ATP-dependent chromatin remodelling enzymes (remodellers) regulate DNA accessibility in eukaryotic genomes. Many remodellers reposition (slide) nucleosomes, however, how DNA is propagated around the histone octamer during this process is unclear. Here we examine the real-time coordination of remodel...
Autores principales: | Sabantsev, Anton, Levendosky, Robert F., Zhuang, Xiaowei, Bowman, Gregory D., Deindl, Sebastian |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6461674/ https://www.ncbi.nlm.nih.gov/pubmed/30979890 http://dx.doi.org/10.1038/s41467-019-09657-1 |
Ejemplares similares
-
The Chd1 chromatin remodeler shifts hexasomes unidirectionally
por: Levendosky, Robert F, et al.
Publicado: (2016) -
Asymmetry between the two acidic patches dictates the direction of nucleosome sliding by the ISWI chromatin remodeler
por: Levendosky, Robert F, et al.
Publicado: (2019) -
Structure and dynamics of the chromatin remodeler ALC1 bound to a PARylated nucleosome
por: Bacic, Luka, et al.
Publicado: (2021) -
The ATPase motor of the Chd1 chromatin remodeler stimulates DNA unwrapping from the nucleosome
por: Tokuda, Joshua M, et al.
Publicado: (2018) -
Histone H4 tail mediates allosteric regulation of nucleosome remodelling by linker DNA
por: Hwang, William L., et al.
Publicado: (2014)