Mitochondria-specific drug release and reactive oxygen species burst induced by polyprodrug nanoreactors can enhance chemotherapy

Cancer cells exhibit slightly elevated levels of reactive oxygen species (ROS) compared with normal cells, and approximately 90% of intracellular ROS is produced in mitochondria. In situ mitochondrial ROS amplification is a promising strategy to enhance cancer therapy. Here we report cancer cell and...

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Detalles Bibliográficos
Autores principales: Zhang, Wenjia, Hu, Xianglong, Shen, Qi, Xing, Da
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6461692/
https://www.ncbi.nlm.nih.gov/pubmed/30979885
http://dx.doi.org/10.1038/s41467-019-09566-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6461692/
https://www.ncbi.nlm.nih.gov/pubmed/30979885
http://dx.doi.org/10.1038/s41467-019-09566-3

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