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TET3 prevents terminal differentiation of adult NSCs by a non-catalytic action at Snrpn

Ten-eleven-translocation (TET) proteins catalyze DNA hydroxylation, playing an important role in demethylation of DNA in mammals. Remarkably, although hydroxymethylation levels are high in the mouse brain, the potential role of TET proteins in adult neurogenesis is unknown. We show here that a non-c...

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Detalles Bibliográficos
Autores principales: Montalbán-Loro, Raquel, Lozano-Ureña, Anna, Ito, Mitsuteru, Krueger, Christel, Reik, Wolf, Ferguson-Smith, Anne C., Ferrón, Sacri R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6461695/
https://www.ncbi.nlm.nih.gov/pubmed/30979904
http://dx.doi.org/10.1038/s41467-019-09665-1