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TET3 prevents terminal differentiation of adult NSCs by a non-catalytic action at Snrpn
Ten-eleven-translocation (TET) proteins catalyze DNA hydroxylation, playing an important role in demethylation of DNA in mammals. Remarkably, although hydroxymethylation levels are high in the mouse brain, the potential role of TET proteins in adult neurogenesis is unknown. We show here that a non-c...
Autores principales: | Montalbán-Loro, Raquel, Lozano-Ureña, Anna, Ito, Mitsuteru, Krueger, Christel, Reik, Wolf, Ferguson-Smith, Anne C., Ferrón, Sacri R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6461695/ https://www.ncbi.nlm.nih.gov/pubmed/30979904 http://dx.doi.org/10.1038/s41467-019-09665-1 |
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