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Assembly of Human Stem Cell-Derived Cortical Spheroids and Vascular Spheroids to Model 3-D Brain-like Tissues

Human cerebral organoids derived from induced pluripotent stem cells (iPSCs) provide novel tools for recapitulating the cytoarchitecture of human brain and for studying biological mechanisms of neurological disorders. However, the heterotypic interactions of neurovascular units, composed of neurons,...

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Detalles Bibliográficos
Autores principales: Song, Liqing, Yuan, Xuegang, Jones, Zachary, Griffin, Kyle, Zhou, Yi, Ma, Teng, Li, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6461701/
https://www.ncbi.nlm.nih.gov/pubmed/30979929
http://dx.doi.org/10.1038/s41598-019-42439-9