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Assembly of Human Stem Cell-Derived Cortical Spheroids and Vascular Spheroids to Model 3-D Brain-like Tissues
Human cerebral organoids derived from induced pluripotent stem cells (iPSCs) provide novel tools for recapitulating the cytoarchitecture of human brain and for studying biological mechanisms of neurological disorders. However, the heterotypic interactions of neurovascular units, composed of neurons,...
Autores principales: | Song, Liqing, Yuan, Xuegang, Jones, Zachary, Griffin, Kyle, Zhou, Yi, Ma, Teng, Li, Yan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6461701/ https://www.ncbi.nlm.nih.gov/pubmed/30979929 http://dx.doi.org/10.1038/s41598-019-42439-9 |
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