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Myeloid-derived suppressor cells endow stem-like qualities to multiple myeloma cells by inducing piRNA-823 expression and DNMT3B activation

BACKGROUND: Myeloid-derived suppressor cells (MDSCs) and cancer stem cells (CSCs) are two important cellular components in the tumor microenvironment, which may modify the cancer phenotype and affect patient survival. However, the crosstalk between MDSCs and multiple myeloma stem cells (MMSCs) are r...

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Detalles Bibliográficos
Autores principales: Ai, Lisha, Mu, Shidai, Sun, Chunyan, Fan, Fengjuan, Yan, Han, Qin, You, Cui, Guohui, Wang, Yadan, Guo, Tao, Mei, Heng, Wang, Huafang, Hu, Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6461814/
https://www.ncbi.nlm.nih.gov/pubmed/30979371
http://dx.doi.org/10.1186/s12943-019-1011-5