Activation of GPR40 produces mechanical antiallodynia via the spinal glial interleukin-10/β-endorphin pathway

BACKGROUND: The G protein-coupled receptor 40 (GPR40), broadly expressed in various tissues such as the spinal cord, exerts multiple physiological functions including pain regulation. This study aimed to elucidate the mechanisms underlying GPR40 activation-induced antinociception in neuropathic pain...

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Detalles Bibliográficos
Autores principales: Mao, Xiao-Fang, Wu, Hai-Yun, Tang, Xue-Qi, Ali, Usman, Liu, Hao, Wang, Yong-Xiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6461825/
https://www.ncbi.nlm.nih.gov/pubmed/30981281
http://dx.doi.org/10.1186/s12974-019-1457-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6461825/
https://www.ncbi.nlm.nih.gov/pubmed/30981281
http://dx.doi.org/10.1186/s12974-019-1457-9

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