Cargando…
Regulating BRCA1 protein stability by cathepsin S-mediated ubiquitin degradation
Cathepsin S (CTSS) is a cysteine protease that is thought to play a role in many physiological and pathological processes including tumor growth, angiogenesis, and metastasis; it has been identified as a radiation response gene. Here, we examined the role of CTSS in regulating the DNA damage respons...
Autores principales: | , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6461859/ https://www.ncbi.nlm.nih.gov/pubmed/30006610 http://dx.doi.org/10.1038/s41418-018-0153-0 |