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Regulating BRCA1 protein stability by cathepsin S-mediated ubiquitin degradation

Cathepsin S (CTSS) is a cysteine protease that is thought to play a role in many physiological and pathological processes including tumor growth, angiogenesis, and metastasis; it has been identified as a radiation response gene. Here, we examined the role of CTSS in regulating the DNA damage respons...

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Detalles Bibliográficos
Autores principales: Kim, SeoYoung, Jin, Hee, Seo, Hang-Rhan, Lee, Hae June, Lee, Yun-Sil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6461859/
https://www.ncbi.nlm.nih.gov/pubmed/30006610
http://dx.doi.org/10.1038/s41418-018-0153-0