Low-dose decitabine enhances the effect of PD-1 blockade in colorectal cancer with microsatellite stability by re-modulating the tumor microenvironment

PD-1 blockade has demonstrated impressive clinical outcomes in colorectal cancers that have high microsatellite instability. However, the therapeutic efficacy for patients with tumors with low microsatellite instability or stable microsatellites needs further improvement. Here, we have demonstrated...

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Detalles Bibliográficos
Autores principales: Yu, Ganjun, Wu, Yanfeng, Wang, Wenying, Xu, Jia, Lv, Xiaoping, Cao, Xuetao, Wan, Tao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6461874/
https://www.ncbi.nlm.nih.gov/pubmed/29622799
http://dx.doi.org/10.1038/s41423-018-0026-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6461874/
https://www.ncbi.nlm.nih.gov/pubmed/29622799
http://dx.doi.org/10.1038/s41423-018-0026-y

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