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Molecular heterogeneity and early metastatic clone selection in testicular germ cell cancer development

BACKGROUND: Testicular germ cell cancer (TGCC), being the most frequent malignancy in young Caucasian males, is initiated from an embryonic germ cell. This study determines intratumour heterogeneity to unravel tumour progression from initiation until metastasis. METHODS: In total, 42 purified sample...

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Detalles Bibliográficos
Autores principales: Dorssers, Lambert C. J., Gillis, Ad J. M., Stoop, Hans, van Marion, Ronald, Nieboer, Marleen M., van Riet, Job, van de Werken, Harmen J. G., Oosterhuis, J. Wolter, de Ridder, Jeroen, Looijenga, Leendert H. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6461884/
https://www.ncbi.nlm.nih.gov/pubmed/30739914
http://dx.doi.org/10.1038/s41416-019-0381-1