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Differential effects, on oncogenic pathway signalling, by derivatives of the HNF4 α inhibitor BI6015

BACKGROUND: Gastric cancer (GC) is a highly heterogeneous disease with few “targeted” therapeutic options. Previously, we demonstrated involvement of the transcription factor HNF4α in human GC tumours, and the developmental signal mediator, WNT5A, as a prognostic GC biomarker. One previously develop...

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Detalles Bibliográficos
Autores principales: Kim, Jin-Hee, Eom, Hyo Jin, Lim, GyuTae, Park, Sungjin, Lee, Jinhyuk, Nam, Seungyoon, Kim, Yon Hui, Jeong, Jin-Hyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6461897/
https://www.ncbi.nlm.nih.gov/pubmed/30792535
http://dx.doi.org/10.1038/s41416-018-0374-5