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Differential effects, on oncogenic pathway signalling, by derivatives of the HNF4 α inhibitor BI6015
BACKGROUND: Gastric cancer (GC) is a highly heterogeneous disease with few “targeted” therapeutic options. Previously, we demonstrated involvement of the transcription factor HNF4α in human GC tumours, and the developmental signal mediator, WNT5A, as a prognostic GC biomarker. One previously develop...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6461897/ https://www.ncbi.nlm.nih.gov/pubmed/30792535 http://dx.doi.org/10.1038/s41416-018-0374-5 |