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Uneven distribution of cobamide biosynthesis and dependence in bacteria predicted by comparative genomics

The vitamin B(12) family of cofactors known as cobamides are essential for a variety of microbial metabolisms. We used comparative genomics of 11,000 bacterial species to analyze the extent and distribution of cobamide production and use across bacteria. We find that 86% of bacteria in this data set...

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Detalles Bibliográficos
Autores principales: Shelton, Amanda N., Seth, Erica C., Mok, Kenny C., Han, Andrew W., Jackson, Samantha N., Haft, David R., Taga, Michiko E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6461909/
https://www.ncbi.nlm.nih.gov/pubmed/30429574
http://dx.doi.org/10.1038/s41396-018-0304-9