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Uneven distribution of cobamide biosynthesis and dependence in bacteria predicted by comparative genomics
The vitamin B(12) family of cofactors known as cobamides are essential for a variety of microbial metabolisms. We used comparative genomics of 11,000 bacterial species to analyze the extent and distribution of cobamide production and use across bacteria. We find that 86% of bacteria in this data set...
Autores principales: | Shelton, Amanda N., Seth, Erica C., Mok, Kenny C., Han, Andrew W., Jackson, Samantha N., Haft, David R., Taga, Michiko E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6461909/ https://www.ncbi.nlm.nih.gov/pubmed/30429574 http://dx.doi.org/10.1038/s41396-018-0304-9 |
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