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Low-dose anti-inflammatory combinatorial therapy reduced cancer stem cell formation in patient-derived preclinical models for tumour relapse prevention

BACKGROUND: Emergence of drug-resistant cancer phenotypes is a challenge for anti-cancer therapy. Cancer stem cells are identified as one of the ways by which chemoresistance develops. METHOD: We investigated the anti-inflammatory combinatorial treatment (DA) of doxorubicin and aspirin using a precl...

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Detalles Bibliográficos
Autores principales: Khoo, Bee Luan, Grenci, Gianluca, Lim, Joey Sze Yun, Lim, Yan Ping, Fong, July, Yeap, Wei Hseun, Bin Lim, Su, Chua, Song Lin, Wong, Siew Cheng, Yap, Yoon-Sim, Lee, Soo Chin, Lim, Chwee Teck, Han, Jongyoon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6461953/
https://www.ncbi.nlm.nih.gov/pubmed/30713340
http://dx.doi.org/10.1038/s41416-018-0301-9