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Low-dose anti-inflammatory combinatorial therapy reduced cancer stem cell formation in patient-derived preclinical models for tumour relapse prevention
BACKGROUND: Emergence of drug-resistant cancer phenotypes is a challenge for anti-cancer therapy. Cancer stem cells are identified as one of the ways by which chemoresistance develops. METHOD: We investigated the anti-inflammatory combinatorial treatment (DA) of doxorubicin and aspirin using a precl...
Autores principales: | Khoo, Bee Luan, Grenci, Gianluca, Lim, Joey Sze Yun, Lim, Yan Ping, Fong, July, Yeap, Wei Hseun, Bin Lim, Su, Chua, Song Lin, Wong, Siew Cheng, Yap, Yoon-Sim, Lee, Soo Chin, Lim, Chwee Teck, Han, Jongyoon |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6461953/ https://www.ncbi.nlm.nih.gov/pubmed/30713340 http://dx.doi.org/10.1038/s41416-018-0301-9 |
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