The lncRNA HOTAIR transcription is controlled by HNF4α-induced chromatin topology modulation

The expression of the long noncoding RNA HOTAIR (HOX Transcript Antisense Intergenic RNA) is largely deregulated in epithelial cancers and positively correlates with poor prognosis and progression of hepatocellular carcinoma and gastrointestinal cancers. Furthermore, functional studies revealed a pi...

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Detalles Bibliográficos
Autores principales: Battistelli, Cecilia, Sabarese, Giovanna, Santangelo, Laura, Montaldo, Claudia, Gonzalez, Frank J., Tripodi, Marco, Cicchini, Carla
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6461983/
https://www.ncbi.nlm.nih.gov/pubmed/30154449
http://dx.doi.org/10.1038/s41418-018-0170-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6461983/
https://www.ncbi.nlm.nih.gov/pubmed/30154449
http://dx.doi.org/10.1038/s41418-018-0170-z

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