Cargando…

The lncRNA HOTAIR transcription is controlled by HNF4α-induced chromatin topology modulation

The expression of the long noncoding RNA HOTAIR (HOX Transcript Antisense Intergenic RNA) is largely deregulated in epithelial cancers and positively correlates with poor prognosis and progression of hepatocellular carcinoma and gastrointestinal cancers. Furthermore, functional studies revealed a pi...

Descripción completa

Detalles Bibliográficos
Autores principales:	Battistelli, Cecilia, Sabarese, Giovanna, Santangelo, Laura, Montaldo, Claudia, Gonzalez, Frank J., Tripodi, Marco, Cicchini, Carla
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6461983/ https://www.ncbi.nlm.nih.gov/pubmed/30154449 http://dx.doi.org/10.1038/s41418-018-0170-z

Ejemplares similares

lncRNA HOTAIR functions and therapeutic perspectives
por: Garbo, Sabrina, et al.
Publicado: (2022)

The Snail repressor recruits EZH2 to specific genomic sites through the enrollment of the lncRNA HOTAIR in epithelial-to-mesenchymal transition
por: Battistelli, C, et al.
Publicado: (2017)

The lncRNA HOTAIR: a pleiotropic regulator of epithelial cell plasticity
por: Amicone, Laura, et al.
Publicado: (2023)

YAP integrates the regulatory Snail/HNF4α circuitry controlling epithelial/hepatocyte differentiation
por: Noce, Valeria, et al.
Publicado: (2019)

LncRNA HOTAIR recruits SNAIL to inhibit the transcription of HNF4α and promote the viability, migration, invasion and EMT of colorectal cancer
por: Jin, Long, et al.
Publicado: (2021)

Functional Roles and Therapeutic Applications of Exosomes in Hepatocellular Carcinoma
por: Santangelo, Laura, et al.
Publicado: (2017)

TGFβ Impairs HNF1α Functional Activity in Epithelial-to-Mesenchymal Transition Interfering With the Recruitment of CBP/p300 Acetyltransferases
por: Bisceglia, Francesca, et al.
Publicado: (2019)

Targeting of polycombs to DNA in EMT
por: Battistelli, Cecilia, et al.
Publicado: (2017)

Functions of lncRNA HOTAIR in lung cancer
por: Loewen, Gregory, et al.
Publicado: (2014)

HOTAIR lncRNA promotes epithelial–mesenchymal transition by redistributing LSD1 at regulatory chromatin regions
por: Jarroux, Julien, et al.
Publicado: (2021)

LncRNA HOTAIR in Tumor Microenvironment: What Role?
por: Botti, Gerardo, et al.
Publicado: (2019)

Genetic variants of lncRNA HOTAIR contribute to the risk of osteosarcoma
por: Zhou, Quan, et al.
Publicado: (2016)

LncRNA Hnf4αos exacerbates liver ischemia/reperfusion injury in mice via Hnf4αos/Hnf4α duplex-mediated PGC1α suppression
por: Wang, Chaoqun, et al.
Publicado: (2022)

LncRNA PACER is down-regulated in osteoarthritis and regulates chondrocyte apoptosis and lncRNA HOTAIR expression
por: Jiang, Mingwei, et al.
Publicado: (2019)

Extracellular signal-Regulated Kinase 5 (ERK5) is required for the Yes-associated protein (YAP) co-transcriptional activity
por: Ippolito, Francesca, et al.
Publicado: (2023)

SYNCRIP Modulates the Epithelial-Mesenchymal Transition in Hepatocytes and HCC Cells
por: Riccioni, Veronica, et al.
Publicado: (2022)

The HASTER lncRNA promoter is a cis-acting transcriptional stabilizer of HNF1A
por: Beucher, Anthony, et al.
Publicado: (2022)

Functional polymorphisms in LncRNA HOTAIR contribute to susceptibility of pancreatic cancer
por: Jiang, Dawei, et al.
Publicado: (2019)

Functions and underlying mechanisms of lncRNA HOTAIR in cancer chemotherapy resistance
por: Zhu, Chunming, et al.
Publicado: (2022)

The HNF1α-regulated lncRNA HNF1A-AS1 reverses the malignancy of hepatocellular carcinoma by enhancing the phosphatase activity of SHP-1
por: Ding, Chen-Hong, et al.
Publicado: (2018)

JMJD6–BRD4 complex stimulates lncRNA HOTAIR transcription by binding to the promoter region of HOTAIR and induces radioresistance in liver cancer stem cells
por: Pei, Ruifeng, et al.
Publicado: (2023)

LncRNA HOTAIR Enhances the Androgen-Receptor-Mediated Transcriptional Program and Drives Castration-Resistant Prostate Cancer
por: Zhang, Ali, et al.
Publicado: (2015)

Circulating HOTAIR LncRNA Is Potentially Up-regulated in Coronary Artery Disease
por: Avazpour, Niloofar, et al.
Publicado: (2018)

Prognostic Value of LncRNA HOTAIR in Colorectal Cancer: A Meta-analysis
por: Chen, Shuangqian, et al.
Publicado: (2020)

lncRNA HOTAIR knockdown suppresses gastric cancer cell biological activities
por: Chao, Pan, et al.
Publicado: (2020)

The HOTAIR lncRNA: A remarkable oncogenic promoter in human cancer metastasis
por: Chen, Lili, et al.
Publicado: (2021)

Association between HOTAIR lncRNA Polymorphisms and Coronary Artery Disease Susceptibility
por: Kim, In-Jai, et al.
Publicado: (2021)

The diagnostic value of lncRNA HOTAIR for cervical carcinoma in vaginal discharge and serum
por: Liu, Ming-Yan, et al.
Publicado: (2023)

The ratio of FoxA1 to FoxA2 in lung adenocarcinoma is regulated by LncRNA HOTAIR and chromatin remodeling factor LSH
por: Wang, Ranran, et al.
Publicado: (2015)

LncRNA PTCSC3 inhibits cell proliferation in laryngeal squamous cell carcinoma by down-regulating lncRNA HOTAIR
por: Xiao, Dong, et al.
Publicado: (2019)

H19 lncRNA alters methylation and expression of Hnf4α in the liver of metformin-exposed fetuses
por: Deng, Jie, et al.
Publicado: (2017)

LncRNA HOTAIR enhances ER signaling and confers tamoxifen resistance in breast cancer
por: Xue, Xingyang, et al.
Publicado: (2015)

Onco-lncRNA HOTAIR and its functional genetic variants in papillary thyroid carcinoma
por: Zhu, Hui, et al.
Publicado: (2016)

The lncRNA HOTAIR impacts on mesenchymal stem cells via triple helix formation
por: Kalwa, Marie, et al.
Publicado: (2016)

LncRNA HOTAIR regulates lipopolysaccharide-induced cytokine expression and inflammatory response in macrophages
por: Obaid, Monira, et al.
Publicado: (2018)

Osteopontin‐induced lncRNA HOTAIR expression is involved in osteoarthritis by regulating cell proliferation
por: Liang, Quanzhi, et al.
Publicado: (2021)

Investigating the effect of lncRNA HOTAIR on apoptosis induced by myocardial ischemia-reperfusion injury
por: Fang, Jijing, et al.
Publicado: (2021)

Genetic impacts on thermostability of onco-lncRNA HOTAIR during the development and progression of endometriosis
por: Chang, Cherry Yin-Yi, et al.
Publicado: (2021)

LncRNA HOTAIR: A Potential Prognostic Factor and Therapeutic Target in Human Cancers
por: Xin, Xiaoru, et al.
Publicado: (2021)

Correction: H19 lncRNA alters methylation and expression of Hnf4α in the liver of metformin-exposed fetuses
por: Deng, Jie, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_a9plc1v6rf5qvn14n3c7ba8jqn