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Comparison of methods for multivariate gene-based association tests for complex diseases using common variants

Complex diseases are usually associated with multiple correlated phenotypes, and the analysis of composite scores or disease status may not fully capture the complexity (or multidimensionality). Joint analysis of multiple disease-related phenotypes in genetic tests could potentially increase power t...

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Detalles Bibliográficos
Autores principales: Chung, Jaeyoon, Jun, Gyungah R., Dupuis, Josée, Farrer, Lindsay A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6461986/
https://www.ncbi.nlm.nih.gov/pubmed/30683923
http://dx.doi.org/10.1038/s41431-018-0327-8