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Comparison of methods for multivariate gene-based association tests for complex diseases using common variants
Complex diseases are usually associated with multiple correlated phenotypes, and the analysis of composite scores or disease status may not fully capture the complexity (or multidimensionality). Joint analysis of multiple disease-related phenotypes in genetic tests could potentially increase power t...
Autores principales: | Chung, Jaeyoon, Jun, Gyungah R., Dupuis, Josée, Farrer, Lindsay A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6461986/ https://www.ncbi.nlm.nih.gov/pubmed/30683923 http://dx.doi.org/10.1038/s41431-018-0327-8 |
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