A novel approach to modelling transcriptional heterogeneity identifies the oncogene candidate CBX2 in invasive breast carcinoma

BACKGROUND: Oncogenes promote the development of therapeutic targets against subsets of cancers. Only several hundred oncogenes have been identified, primarily via mutation-based approaches, in the human genome. Transcriptional overexpression is a less-explored mechanism through which oncogenes can...

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Detalles Bibliográficos
Autores principales: Piqué, Daniel G., Montagna, Cristina, Greally, John M., Mar, Jessica C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6462018/
https://www.ncbi.nlm.nih.gov/pubmed/30820027
http://dx.doi.org/10.1038/s41416-019-0387-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6462018/
https://www.ncbi.nlm.nih.gov/pubmed/30820027
http://dx.doi.org/10.1038/s41416-019-0387-8

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