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A novel approach to modelling transcriptional heterogeneity identifies the oncogene candidate CBX2 in invasive breast carcinoma
BACKGROUND: Oncogenes promote the development of therapeutic targets against subsets of cancers. Only several hundred oncogenes have been identified, primarily via mutation-based approaches, in the human genome. Transcriptional overexpression is a less-explored mechanism through which oncogenes can...
Autores principales: | Piqué, Daniel G., Montagna, Cristina, Greally, John M., Mar, Jessica C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6462018/ https://www.ncbi.nlm.nih.gov/pubmed/30820027 http://dx.doi.org/10.1038/s41416-019-0387-8 |
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