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Structure of HIV-1 RT/dsRNA initiation complex prior to nucleotide incorporation
The initiation phase of HIV reverse transcription has features that are distinct from its elongation phase. The first structure of a reverse transcription initiation complex (RTIC) that trapped the complex after incorporation of one ddCMP nucleotide was published recently [Larsen KP, et al. (2018) N...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6462067/ https://www.ncbi.nlm.nih.gov/pubmed/30902895 http://dx.doi.org/10.1073/pnas.1814170116 |