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Acquisition of a hybrid E/M state is essential for tumorigenicity of basal breast cancer cells

Carcinoma cells residing in an intermediate phenotypic state along the epithelial–mesenchymal (E–M) spectrum are associated with malignant phenotypes, such as invasiveness, tumor-initiating ability, and metastatic dissemination. Using the recently described CD104(+)/CD44(hi) antigen marker combinati...

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Detalles Bibliográficos
Autores principales: Kröger, Cornelia, Afeyan, Alexander, Mraz, Jasmin, Eaton, Elinor Ng, Reinhardt, Ferenc, Khodor, Yevgenia L., Thiru, Prathapan, Bierie, Brian, Ye, Xin, Burge, Christopher B., Weinberg, Robert A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6462070/
https://www.ncbi.nlm.nih.gov/pubmed/30910979
http://dx.doi.org/10.1073/pnas.1812876116