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Acquisition of a hybrid E/M state is essential for tumorigenicity of basal breast cancer cells
Carcinoma cells residing in an intermediate phenotypic state along the epithelial–mesenchymal (E–M) spectrum are associated with malignant phenotypes, such as invasiveness, tumor-initiating ability, and metastatic dissemination. Using the recently described CD104(+)/CD44(hi) antigen marker combinati...
Autores principales: | Kröger, Cornelia, Afeyan, Alexander, Mraz, Jasmin, Eaton, Elinor Ng, Reinhardt, Ferenc, Khodor, Yevgenia L., Thiru, Prathapan, Bierie, Brian, Ye, Xin, Burge, Christopher B., Weinberg, Robert A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6462070/ https://www.ncbi.nlm.nih.gov/pubmed/30910979 http://dx.doi.org/10.1073/pnas.1812876116 |
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