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Glucocorticoid Receptor–Tethered Mineralocorticoid Receptors Increase Glucocorticoid-Induced Transcriptional Responses

Mineralocorticoid and glucocorticoid receptors (MRs and GRs) constitute a functionally important dual receptor system detecting and transmitting circulating corticosteroid signals. High expression of MRs and GRs occurs in the same cells in the limbic system, the primary site of glucocorticoid action...

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Detalles Bibliográficos
Autores principales: Rivers, Caroline A, Rogers, Mark F, Stubbs, Felicity E, Conway-Campbell, Becky L, Lightman, Stafford L, Pooley, John R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Endocrine Society 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6462215/
https://www.ncbi.nlm.nih.gov/pubmed/30980716
http://dx.doi.org/10.1210/en.2018-00819