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Flagellin-mediated activation of IL-33-ST2 signaling by a pathobiont promotes intestinal fibrosis

Intestinal fibrosis is a severe complication in patients with Crohn’s disease (CD). Unfortunately, the trigger leading to the development of intestinal fibrosis in the context of CD remains elusive. Here, we show that colonization by a CD-associated pathobiont adherent-invasive Escherichia coli (AIE...

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Detalles Bibliográficos
Autores principales: Imai, Jin, Kitamoto, Sho, Sugihara, Kohei, Nagao-Kitamoto, Hiroko, Hayashi, Atsushi, Morhardt, Tina L., Kuffa, Peter, Higgins, Peter D. R., Barnich, Nicolas, Kamada, Nobuhiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6462251/
https://www.ncbi.nlm.nih.gov/pubmed/30742042
http://dx.doi.org/10.1038/s41385-019-0138-4