Hydroalcoholic Extract of Levisticum officinale Increases cGMP Signaling Pathway by Down-Regulating PDE5 Expression and Induction of Apoptosis in MCF-7 and MDA-MB-468 Breast Cancer Cell Lines

BACKGROUND: This study aimed to investigate Levisticum officinale hydroalcoholic extract (LOHE) effect on both cGMP signaling pathway and phosphodiesterase 5 (PDE5) gene expression pattern and to examine the role of LOHE in apoptosis induction of MCF-7 and MDA-MB-468 cell lines. METHODS: The half ma...

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Detalles Bibliográficos
Autores principales: Sargazi, Marzieh Lotfian, Saravani, Ramin, Shahraki, Ali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Pasteur Institute 2019
Materias:
Full Length
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6462291/
https://www.ncbi.nlm.nih.gov/pubmed/30388886
http://dx.doi.org/10.29252/.23.4.280

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6462291/
https://www.ncbi.nlm.nih.gov/pubmed/30388886
http://dx.doi.org/10.29252/.23.4.280

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