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Small-Volume Flow Cytometry-Based Multiplex Analysis of the Activity of Small GTPases

Small, monomeric guanine triphosphate hydrolases (GTPases) are ubiquitous cellular integrators of signaling. A signal activates the GTPase, which then binds to an effector molecule to relay a signal inside the cell. The GTPase effector trap flow cytometry assay (G-Trap) utilizes bead-based protein i...

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Detalles Bibliográficos
Autores principales: Simons, Peter, Bondu, Virginie, Wandinger-Ness, Angela, Buranda, Tione
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6462310/
https://www.ncbi.nlm.nih.gov/pubmed/30062413
http://dx.doi.org/10.1007/978-1-4939-8612-5_13