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BRM270 Inhibits the Proliferation of CD44 Positive Pancreatic Ductal Adenocarcinoma Cells via Downregulation of Sonic Hedgehog Signaling

Pancreatic cancer has a poor survival rate as compared to other types of cancer. Surface marker CD44 plays important role in epithelial-mesenchymal transition and cancer stem cell phenotype. Therefore, targeting CD44 positive pancreatic cancer cells might enhance therapies effectiveness. Our previou...

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Detalles Bibliográficos
Autores principales: Huynh, Do Luong, Koh, Hyebin, Chandimali, Nisansala, Zhang, Jiao Jiao, Kim, Nameun, Kang, Tae Yoon, Ghosh, Mrinmoy, Gera, Meeta, Park, Yang-Ho, Kwon, Taeho, Jeong, Dong Kee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6462339/
https://www.ncbi.nlm.nih.gov/pubmed/31049070
http://dx.doi.org/10.1155/2019/8620469