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Neuron-Derived Estrogen Regulates Synaptic Plasticity and Memory
17β-estradiol (E2) is produced from androgens via the action of the enzyme aromatase. E2 is known to be made in neurons in the brain, but its precise functions in the brain are unclear. Here, we used a forebrain-neuron-specific aromatase knock-out (FBN-ARO-KO) mouse model to deplete neuron-derived E...
Autores principales: | Lu, Yujiao, Sareddy, Gangadhara R., Wang, Jing, Wang, Ruimin, Li, Yong, Dong, Yan, Zhang, Quanguang, Liu, Jinyou, O'Connor, Jason C., Xu, Jianhua, Vadlamudi, Ratna K., Brann, Darrell W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Society for Neuroscience
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6462452/ https://www.ncbi.nlm.nih.gov/pubmed/30728170 http://dx.doi.org/10.1523/JNEUROSCI.1970-18.2019 |
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