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Dopamine transporter forms stable dimers in the live cell plasma membrane in a phosphatidylinositol 4,5-bisphosphate–independent manner

The human dopamine transporter (hDAT) regulates the level of the neurotransmitter dopamine (DA) in the synaptic cleft and recycles DA for storage in the presynaptic vesicular pool. Many neurotransmitter transporters exist as oligomers, but the physiological role of oligomerization remains unclear; f...

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Detalles Bibliográficos
Autores principales: Das, Anand Kant, Kudlacek, Oliver, Baumgart, Florian, Jaentsch, Kathrin, Stockner, Thomas, Sitte, Harald H., Schütz, Gerhard J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6462504/
https://www.ncbi.nlm.nih.gov/pubmed/30705091
http://dx.doi.org/10.1074/jbc.RA118.006178