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Fibrinogen αC domain: Its importance in physiopathology

ESSENTIALS: The C‐terminal domain of the fibrinogen α chain (αC domain) is implicated in different severe diseases via clotting abnormalities or amyloid deposits. Certain anomalies of the fibrinogen molecule lead to amyloid deposits in the kidney, inducing renal insufficiency. In contrast, in Alzhei...

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Detalles Bibliográficos
Autores principales: Soria, Jeannette, Mirshahi, Shahsoltan, Mirshahi, Sam Qiumars, Varin, Remi, Pritchard, Linda L., Soria, Claudine, Mirshahi, Massoud
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6462745/
https://www.ncbi.nlm.nih.gov/pubmed/31011701
http://dx.doi.org/10.1002/rth2.12183