Shear stress and platelet‐induced tensile forces regulate ADAMTS13‐localization within the platelet thrombus

BACKGROUND: The multimeric glycoprotein von Willebrand factor (VWF) mediates platelet adhesion and aggregation at the site of vessel injury. The adhesive activity of VWF is influenced by its multimer length which is regulated by the metalloprotease ADAMTS13. The ability of ADAMTS13 to regulate plate...

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Detalles Bibliográficos
Autores principales: Shida, Yasuaki, Swystun, Laura L., Brown, Christine, Mewburn, Jeffrey, Nesbitt, Kate, Danisment, Ozge, Riches, Jonathan Jacob, Hough, Christine, Lillicrap, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Original Articles: Haemostasis
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6462754/
https://www.ncbi.nlm.nih.gov/pubmed/31011709
http://dx.doi.org/10.1002/rth2.12196

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6462754/
https://www.ncbi.nlm.nih.gov/pubmed/31011709
http://dx.doi.org/10.1002/rth2.12196

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