Cost-effectiveness of HLA-DQB1/HLA-B pharmacogenetic-guided treatment and blood monitoring in US patients taking clozapine

Less than 1% of adult patients with schizophrenia taking clozapine develop agranulocytosis, and most of these cases occur within the first weeks of treatment. The human leukocyte antigen (HLA) region has been associated with genetic susceptibility to clozapine-induced agranulocytosis (single amino a...

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Detalles Bibliográficos
Autores principales: Girardin, François R., Poncet, Antoine, Perrier, Arnaud, Vernaz, Nathalie, Pletscher, Mark, F. Samer, Caroline, Lieberman, Jeffrey A., Villard, Jean
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6462824/
https://www.ncbi.nlm.nih.gov/pubmed/29298994
http://dx.doi.org/10.1038/s41397-017-0004-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6462824/
https://www.ncbi.nlm.nih.gov/pubmed/29298994
http://dx.doi.org/10.1038/s41397-017-0004-2

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