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Regulation of human glioma cell migration, tumor growth, and stemness gene expression using a Lck targeted inhibitor

Migration of human glioma cells (hGCs) within the brain parenchyma makes glioblastoma one of the most aggressive and lethal tumors. Studies of the cellular and molecular mechanisms underlying hGC migration are hindered by the limitations of existing glioma models. Here we developed a dorsal root gan...

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Detalles Bibliográficos
Autores principales: Zepecki, J. P., Snyder, K. M., Moreno, M. M., Fajardo, E., Fiser, A., Ness, J., Sarkar, A., Toms, S. A., Tapinos, N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6462869/
https://www.ncbi.nlm.nih.gov/pubmed/30353164
http://dx.doi.org/10.1038/s41388-018-0546-z