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Combined Treatment with Doxorubicin and Rapamycin Is Effective against In Vitro and In Vivo Models of Human Glioblastoma

Despite numerous clinical trials, glioblastoma (GBM) remains a tumor that is difficult to treat. The aim of this study was to investigate the potential of a new pharmacological approach, combining doxorubicin (Dox) and rapamycin (Rapa), in in vitro and in vivo GBM models. Cytotoxic and anti-prolifer...

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Detalles Bibliográficos
Autores principales: Iorio, Anna Lisa, Da Ros, Martina, Pisano, Claudio, de Martino, Maurizio, Genitori, Lorenzo, Sardi, Iacopo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6462908/
https://www.ncbi.nlm.nih.gov/pubmed/30857276
http://dx.doi.org/10.3390/jcm8030331