Gene Expression Changes Associated with Nintedanib Treatment in Idiopathic Pulmonary Fibrosis Fibroblasts: A Next-Generation Sequencing and Bioinformatics Study

Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive, and fatal interstitial lung disease. Therapeutic options for IPF remain limited. Nintedanib, a tyrosine kinase inhibitor approved for IPF treatment, is known to inhibit fibroblasts proliferation, migration and transformation to myofibrob...

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Detalles Bibliográficos
Autores principales: Sheu, Chau-Chyun, Chang, Wei-An, Tsai, Ming-Ju, Liao, Ssu-Hui, Chong, Inn-Wen, Kuo, Po-Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6462954/
https://www.ncbi.nlm.nih.gov/pubmed/30841487
http://dx.doi.org/10.3390/jcm8030308

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6462954/
https://www.ncbi.nlm.nih.gov/pubmed/30841487
http://dx.doi.org/10.3390/jcm8030308

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