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Supercoil Levels in E. coli and Salmonella Chromosomes Are Regulated by the C-Terminal 35–38 Amino Acids of GyrA

Prokaryotes have an essential gene—gyrase—that catalyzes negative supercoiling of plasmid and chromosomal DNA. Negative supercoils influence DNA replication, transcription, homologous recombination, site-specific recombination, genetic transposition and sister chromosome segregation. Although E. col...

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Detalles Bibliográficos
Autores principales: Rovinskiy, Nikolay S., Agbleke, Andrews A., Chesnokova, Olga N., Higgins, N. Patrick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6463007/
https://www.ncbi.nlm.nih.gov/pubmed/30875939
http://dx.doi.org/10.3390/microorganisms7030081