Epigenetic Changes at the Birc5 Promoter Induced by YM155 in Synovial Sarcoma

YM155 is an anti-cancer therapy that has advanced into 11 different human clinical trials to treat various cancers. This apoptosis-inducing therapy indirectly affects the protein levels of survivin (gene: Birc5), but the molecular underpinnings of the mechanism remain largely unknown. Synovial sarco...

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Detalles Bibliográficos
Autores principales: Mika, Aleksander, Luelling, Sarah E., Pavek, Adriene, Nartker, Christopher, Heyneman, Alexandra L., Jones, Kevin B., Barrott, Jared J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6463023/
https://www.ncbi.nlm.nih.gov/pubmed/30909651
http://dx.doi.org/10.3390/jcm8030408

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6463023/
https://www.ncbi.nlm.nih.gov/pubmed/30909651
http://dx.doi.org/10.3390/jcm8030408

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