SUMOylation promotes protective responses to DNA‐protein crosslinks

DNA‐protein crosslinks (DPCs) are highly cytotoxic lesions that obstruct essential DNA transactions and whose resolution is critical for cell and organismal fitness. However, the mechanisms by which cells respond to and overcome DPCs remain incompletely understood. Recent studies unveiled a dedicate...

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Detalles Bibliográficos
Autores principales: Borgermann, Nikoline, Ackermann, Leena, Schwertman, Petra, Hendriks, Ivo A, Thijssen, Karen, Liu, Julio CY, Lans, Hannes, Nielsen, Michael L, Mailand, Niels
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6463212/
https://www.ncbi.nlm.nih.gov/pubmed/30914427
http://dx.doi.org/10.15252/embj.2019101496

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6463212/
https://www.ncbi.nlm.nih.gov/pubmed/30914427
http://dx.doi.org/10.15252/embj.2019101496

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